Pharmacy500 Market Threats Report 2025

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©2025 RXinsider | RXinsider Market Intelligence Group | 2025

CORE

THEMES

Allegations of

antitrust, false claims,

and public nuisance

violations

Government audits

and investigations

Litigation, including

class actions,

intellectual property

disputes, and opioid

lawsuits

Key Risk Drivers:

• Ongoing and emerging government scrutiny

(FDA, DEA, HHS, DOJ)

• Complex and changing regulatory frameworks

(HIPAA, FCPA, state laws)

• Allegations of healthcare fraud, false claims, or

negligence

• Rising litigation in opioid distribution and public

nuisance claims

• Unpredictable legal outcomes that can escalate

exposure

Strategic Implications:

• Loss of licenses or access to key federal

programs (e.g., Medicare/Medicaid)

• Substantial legal and compliance costs that

strain margins

• Long-term reputational damage, eroding

customer and stakeholder trust

• Increased need for rigorous compliance and

risk management frameworks

Data privacy,

cybersecurity, and

HIPAA compliance

Healthcare fraud

and abuse

3. Compliance, Regulatory Scrutiny, and

Litigation Exposure

The evolving and complex regulatory environment in the healthcare and pharmaceutical industries

exposes companies to heightened legal, compliance, and litigation risks. Enforcement agencies and

shifting legal frameworks increase the potential for investigations, audits, and litigation. This scrutiny can

lead to significant financial burdens, reputational damage, and operational disruptions.

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