Pharmacy500 Reverse Distribution Report 2025

©2025 RXinsider | RXinsider Market Intelligence Group | 2025

EXECUTIVE SNAPSHOT

REVERSE DISTRIBUTION

20% to 25% of total Rx excess inventory may be unsold.

120M

units is the annual volume

of products managed

by reverse distributors.

Source: American Associated Pharmacies

Source: FDA

11

Pharmacy500 companies offering

reverse distribution.

Source: RXinsider

$13B

worth of pharmaceuticals

flow through the reverse

distribution channel.

Source: HDA

Source: American Associated Pharmacies

$11B

of surplus medicine

is wasted annually.

55%

of the 786 households surveyed

kept unused medications at home.

Source: AACI

Source: National Library of Medicine

3.5% to 4% of all pharmaceutical sales accounts

for pharmaceutical returns.

Source: Healthcare Packaging

There were 51 product recalls in the year 2024.