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Pharmacy500 Stock ETF Q2 2025 Report

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Q2 2025

PHARMACY500

PHARMACY500 STOCK ETF

QUARTERLY PERFORMANCE

SHAPSHOT

Report Lead

Lexi Cianfarani

MEET THE

MARKET INTELLIGENCE TEAM

About RXinsider

Founded in 1999, RXinsider is a pharmacist-founded marketing/

communications (MARCOM) and market intelligence (INTEL) company

focused on pharmacy operations and the companies supporting

dispensing pharmacies. Through our publications, digital platforms,

market research, and training resources, RXinsider educates pharmacy

management and industry professionals on the products, services,

and trends that impact pharmacy operations across the supply chain.

RXinsider’s Market Intelligence (INTEL) Group performs market research

on the pharmacy operations supply chain and the Pharmacy500

companies. Through our weekly reports, digital awareness, and online

training, the INTEL Group educates Pharmacy500 professionals and

pharmacy management on the products and services impacting

pharmacy operations.

Alexa DiLuca

Marketing Manager

Gregory Cianfarani, RPh

Founder & CEO

Jeff Rackliff

Pharmacy500 Market Analyst

jeff.rackliff@rxinsider.com

Emma Cidade

Pharmacy500 Market Analyst

emma.cidade@rxinsider.com

Lexi Cianfarani

Pharmacy500 Market Analyst

lexi.cianfarani@rxinsider.com

About the Pharmacy500 Stock ETF

Table of Contents

• Introduction.................................................... 2-3

• Executive Snapshot..........................................4

• Pharmacy500 ETF Companies.......................5

• Portfolio Snapshot.............................................6

• Performance................................................... 7-8

• Benchmarks & Comparisons..........................9

• Stock Blend.......................................................10

• References........................................................11

• Pharmacy500 Companies.......................12-15

What is RXinsider’s Pharmacy500 Stock ETF?

RXinsider’s Pharmacy500 Stock ETF is a stock portfolio

comprised of the largest publicly traded companies in the

Pharmacy500. This ETF (Exchange-Traded Fund) is for

educational and entertainment purposes only and is not

officially registered with the SEC.

What is the history and purpose of the ETF?

On 11/1/2024, RXinsider invested $10,000 in the stock of 11

of the largest companies with a U.S. market presence on the

Pharmacy500 list with the goal of tracking their collective

performance over time and sharing the results with the

pharmacy market.

We also wanted to have a little fun and compare the quarterly

and annual results to other investing benchmarks such as the

S&P500, NASDAQ, and DOW. We felt pharmacy professionals,

pharmacists, and pharmacy students would find this

information both interesting and educational.

What is the methodology for selecting the ETF companies?

More than 40 companies in the Pharmacy500 are publicly

traded companies (the public can purchase company stock).

RXinsider selected the Pharmacy500 companies with the

greatest market cap combined with a significant proportion

of their business focused on pharmacy.

Please note that stock holdings in the ETF are proportional

to the company’s market cap (its overall value). For example,

a greater percentage of the ETF is invested in McKesson vs.

Premier due to McKesson’s larger market cap. Companies

such as CVS Health are not included because they are not a

Pharmacy500 company.

$313.26B

Collective market cap of

all 11 Pharmacy500

ETF companies.

+1.97%

Pharmacy500 Stock ETF

performance against the

S&P500 for Q2 2025.

companies included in the

ETF for 2025.

ETF companies on the

Forbes Fortune500 list.

$91.53B

Market cap of the largest

Pharmacy500 ETF company

(McKesson Corporation).

+10.55%

Total Pharmacy500 ETF gain in

Q2 2025.

EXECUTIVE SNAPSHOT

PHARMACY500

STOCK ETF

Q2 | 2025

+46.96%

The largest individual company

stock gain in YTD 2025

(Cardinal Health).

Companies

Baxter International INC

BAX

270

Medium Cap ($15.54B)

Becton Dickinson & Co

BDX

211

Large Cap ($49.37B)

Cardinal Health Inc

CAH

Medium Cap ($39.98B)

Cencora Inc

COR

Large Cap ($58.12B)

Dexcom Inc

DXCM

N/A

Medium Cap ($34.23B)

Grifols

GRFS

N/A

Small Cap ($2.33B)

ICU Medical Inc

ICUI

N/A

Small Cap ($3.25B)

McKesson Corporation

MCK

Large Cap ($91.53B)

Omnicell

OMCL

N/A

Micro Cap ($1.38B)

Premier Inc

PINC

N/A

Micro Cap ($1.81B)

West Pharmaceutical Services

WST

N/A

Medium Cap ($15.72B)

STOCK SYMBOL

FORTUNE500 RANK

MARKET CAP

Aggregate:

$313.26B (Q2)

Pharmacy500 Stock Portfolio Snapshot

NOV 1, 2024 - JUN 30, 2025 (4:00 PM EST)

Last Quarter Performance

YTD Performance

APR 1, 2025 - JUN 30, 2025 (4:00 PM EST)

JAN 1, 2025 - JUN 30, 2025 (4:00 PM EST)

+9.99%

Time-weighted rate of return (pre-tax)

This

measures

the

cumulative

investment

performance

for

the

quarter. It reflects any growth and

income generated by the investments,

net of fees.

+3.70%

Time-weighted rate of return (pre-tax)

This

measures

the

cumulative

investment performance for the quarter.

It reflects any growth and income

generated by the investments, net of

fees.

All-Time Performance

NOV 1, 2024 - JUN 30, 2025 (4:00 PM EST)

+13.26%

Time-weighted rate of return (pre-tax)

This

measures

the

cumulative

investment

performance

for

the

quarter. It reflects any growth and

income generated by the investments,

net of fees.

Benchmarks & Comparisons

The following snapshot compares the Pharmacy500 Stock

ETF to other financial standards and ETF benchmarks.

S&P 500® Index

The S&P 500® Index is a registered service mark of The McGraw-Hill Companies, Inc., and has been licensed for

use by Fidelity Distributors Corporation and its affiliates. It is an unmanaged market capitalization-weighted index

of 500 common stocks chosen for market size, liquidity, and industry group representation to represent U.S. equity

performance.

Dow Jones U.S. Total Stock Market Index

The Dow Jones US Total Stock Market is an unmanaged float-adjusted market capitalization-weighted index of

substantially all equity securities of U.S. headquartered companies with readily available price data.

Dow Jones Industrial Average

The Dow Jones Industrial Average, published by Dow Jones & Company is an unmanaged average of 30 actively traded

stocks (primarily industrials) that assumes reinvestment of dividends.

Russell 1000 Index

Russell 1000 Index is a market capitalization-weighted index designed to measure the performance of the large-cap

segment of the US equity market.

Fidelity US Total Investable Market Index

The Fidelity U.S. Total Investable Market Index is a float-adjusted market capitalization-weighted index designed to

reflect the performance of the U.S. equity market, including large-, mid- and small-capitalization stocks.

Stock ETF

Stock Blend

We determined that the Pharmacy500 Stock ETF is a medium

blend of stocks. We assessed the 11 stocks and spread them

across two key indicators—market capitalization (Small,

Large, or Mid-sized) and valuation style (Growth, Value, or

Blend) to determine the overall style of those holdings. We

then compared this style to a widely followed benchmark, the

Dow Jones U.S. Total Market Index.

References

Fidelity Investments. (n.d.). Portfolio summary. Retrieved April 1, 2025, from https://digital.

fidelity.com/ftgw/digital/portfolio/summary

Forbes. (n.d.). Forbes. Retrieved April 1, 2025, from https://www.forbes.com/

Disclaimer

This content has been prepared by RXinsider and is based

on secondary market research and analysis of public

information available or provided to RXinsider, including but

not limited to internal data and other references believed to

be true. While every effort is made to ensure the accuracy

and completeness of the information contained, RXinsider

takes no responsibility and assumes no liability for any error/

omission or accuracy of the information.

Recipients of this material should rely on their own judgments

and conclusions from relevant sources. The information

disclosed in this report is provided for general informational

and educational purposes only and is not a substitute

for professional advice. All information in this report is

provided in good faith, however, we make no representation

or warranty of any kind, express or implied, regarding the

accuracy, adequacy, validity, availability, or completeness of

any information. Under no circumstance shall we have any

liability to you for any loss or damage of any kind incurred as

a result of the use of our report.

The information and analysis herein do not constitute advice

of any kind, are not intended to be used for investment

purposes, and neither RXinsider nor any of its subsidiaries or

their respective officers, directors, shareholders, employees

or agents accept any responsibility or liability with respect

to the use of or reliance on any information or analysis

contained in this document.

This work is copyrighted by RXinsider and may not be

published, transmitted, broadcast, copied, reproduced, or

reprinted in whole or in part without the explicit written

permission of RXinsider.

The Pharmacy500 is awarded to 500 pharmacy

supply chain businesses and associations

with the most significant impact on dispensing

pharmacies in the U.S. over the past year. For

Pharmacy500 selection criteria and details,

please visit www.rxinsider.com/Pharmacy500.

AAPA

Abbott | Abbott Diabetes Care

Academy of Managed Care Pharmacy (AMCP)

Accreditation Commission for Health Care

Accreditation Council for Pharmacy Education

Accu-Chart Plus Health Care Systems

Accucold

Acute Care Pharmaceuticals

AdvanceNet Health Solutions

Advasur

Agadia

Air Link International

AirCare Automation

AirClean Systems, Inc.

AIS Healthcare

Akro-Mils

Alliance for Pharmacy Compounding

Allied Pharmacy Products

Altium Packaging

American Analytics

American Associated Pharmacies (AAP)

American Association of Colleges of Pharmacy

American Association of Health System Pharmacists

(ASHP)

American BioTech Supply

American College of Apothecaries

American College of Clinical Pharmacy

American College of Veterinary Pharmacists

American HealthCare Capital

American Pharmacies, Inc.

American Pharmacists Association (APhA)

American Pharmacy Cooperative, Inc. (APCI)

American Rx Group

American Society of Consultant Pharmacists (ASCP)

Americorp Financial, LLC

Amneal Pharmaceuticals LLC

Anda Inc.

AnewHealth

ANiGENT LLC

Animal Med Express

Apexus LLC

Apothecary Products, LLC

APS - Advanced Pharmacy Solutions

ARL Bio Pharma

ARxIUM

Asembia

AssistRx

Associates of Cape Cod, Inc

AssureCare LLC

Asteres Inc.

Athenahealth

Atlas Health

Avel eCare

Aventi Health

Avery Weigh-Tronix | RxSafe/Eyecon

AvKARE, LLC

Azurity Pharmaceuticals, Inc.

Azzur Group

B Medical Systems

B. Braun Medical Inc.

BA Sciences

Baxter

Berkshire Corporation

Berry Global Inc.

BestRx (Redsail)

Beutlich Pharmaceuticals, LLC

BioCareSD

Blue Thunder Technologies Inc.

Bluesight

BluPax Pharma

Board of Certification/Accreditation, International (BOC)

Board of Pharmacy Specialties (BPS)

Bonita Pharmaceuticals

Bureau Veritas

Buy-Sellapharmacy.com

Byline Bank

CAM Commerce Solutions/Celerant Technology

Capital Inventory, Inc

Capital Wholesale Drug Company

Capsa Healthcare

CaptureRx

Cardinal Health

Care Services, LLC.

CarepathRx

CarePoint

CaryHealth

CEImpact

Cencora/AmerisourceBergen

Centor

Central Admixture Pharmacy Services, Inc. (CAPS)

Cervey

Charles River Laboratories

ChemoGLO

CINTAS Corporation

Cipla, Inc.

Civica

Clean Harbors, Inc.

Cleanetics

Cleanroom Connection

Clearway Health

Codonics

Cold Chain Technologies

Coldkeepers

ComCo Systems

CompleteRx

ConsortiEX Inc.

Containment Technologies Group, Inc.

Contec, Inc.

CORE Higher Education Group

CORMED

COSHATT

CoverMyMeds (McKesson Corporation)

CPESN USA, LLC

CPS Solutions, LLC

Crocus Medical Inc.

CuraScriptSD

Cypress Software, Inc.

D2 Solutions

Datarithm

Datascan Pharmacy, Inc.

Dexcom, Inc.

Dickson

Digital Business Solutions, Inc.

DisposeRx, Inc.

DiversifyRx

DocStation

DoseMe

DosePacker, Inc.

DosePlanner

Dr.Reddy’s Laboratories Ltd.

DrFirst

Drugstore2Door

DRX SOFTWARE LLC

Dycem Ltd

Eagle Analytical Services

Ecolab

ECRM

Elsevier

Embecta

Emporos

Endo USA

EnlivenHealth

EPIC Rx

Epic Systems Corporation

Epicor Software Corporation

EQUASHIELD

Esco

Euclid Medical Products

Eurofins Analytics

EveryDose

Everyware

EzriRx

EZSCRIPTRx

Fagron

FFF Enterprises, Inc.

FG Clean Wipes

First Databank, Inc.

First Financial Bank, Inc.

Flash Returns, LLC

FLAVORx

Flexible Pharmacy Services, PLLC

Flowsell

Follett

Franklin Eyewear

Fresenius Kabi Group

Frier Levitt

Fullscript

Genetco Inc.

GeriMed, Inc.

Germfree

Grifols

GRX Marketing

H+H System, Inc.

Hardy Diagnostics

Hayslip Rx Brokers Inc.

HealNow

Health Care Logistics, Inc.

Health Connect Partners, Inc.

HealthTrust

HealthWell Foundation

HelioMetrics

Hematology/Oncology Pharmacy Association (HOPA)

Hikma Pharmaceuticals

ICU Medical

iLocalBox

Imprivata/FairWarning

IND Consulting

Independent Pharmacy Cooperative (IPC)

InfiniTrak, LLC

InfinityLaboratories

InfoWerks

Inmar Inc.

Innovatix, LLC

Inovalon

InsightRX, Inc.

Institute for Safe Medication Practices (ISMP)

InstyMeds

Integrated Medical Systems, Inc. (IMS)

Integrity Pharmacy Consultants

Intelliguard/MEPS Real-Time, Inc.

InTemp Monitoring Solutions

Interlink AI, Inc.

International Journal of Pharmaceutical Compounding

(IJPC)

International Medical Industries

Isak Computing (SiCompounding & SiPrescribe)

ISO-MED, Inc.

IsoTech Design

Jackson Pharmacy Professionals

Jays Company

JFCRx

Jones Healthcare Group

Keycentrix, LLC

KeySource

KNAPP

Labconco

Lakeland Industries, Inc.

Legacy Pharmacy Group

Leiters Health

Liberty Software

Liebherr

LifeFile

Lincoln Savings Bank

Live Oak Bank

Loopback Analytics

LSPedia, Inc.

Lumistry

Lupin Pharmaceuticals Inc.

Managed Health Care Associates, Inc. (MHA)

Manchac Technologies

Masters Pharmaceutical (McKesson Corporation)

MatchRX

Maximum Rx Credit, Inc.

Maxor National Pharmacy Services, LLC

Maxpert Medical

MAXQ

McKesson Corporation

MedAdvisor Solutions (Adheris Health)

Medi-Dose, Inc./EPS, Inc.

Medical Packaging Inc., LLC

Medicine-On-Time

Medigi

Medility Inc.

Medisca Inc.

Meditech

Medivant Healthcare

MediZap

MedMe Health

MedSafety Solutions

Medtel Communications (Lumistry)

MedXL Inc.

Merative

Mesmerize

Micro Merchant Systems, Inc.

MIDAS Healthcare Solutions

Migali Scientific

Mobile MediClaim, Inc.

Moderna, Inc.

Modular Cleanrooms, Inc.

Modular Devices

Modular Pharmacy Solutions, LLC

Morris & Dickson

N3PR

NarcX

National Association of Boards of Pharmacy (NABP)

National Association of Chain Drug Stores (NACDS)

National Association of Specialty Pharmacy (NASP)

National Community Pharmacists Association (NCPA)

National Council for Prescription Drug Programs (NCPDP)

National Home Infusion Association (NHIA)

National Pharmaceutical Returns, Inc.

National Pharmacy Purchasing Association (NPPA)

National Pharmacy Technician Association (NPTA)

Nephron Pharmaceuticals Corporation

Net-Rx (an MHA Solution)

Nimble

Nordic Cold Chain Solutions

Noritsu Pharmacy Automation

NuAire, Inc.

Nuvem

Omega Pharmacy Group

Omnicell

OmniSYS (XiFin Pharmacy Solutions)

Optum, Inc.

Oracle Health/Cerner

OrderInsite, LLC

OurPharma LLC

Outcomes

Owen Mumford

P&C Pharma

PAAS National LLC

Paladin Data Corporation

Paragon Ventures

Parasol Medical, LLC

Parata Systems (BD)

ParcelShield

Patient Access Network Foundation

PCCA

PDM Healthcare

PDR/ConnectiveRx

Pentapack

PEPID, LLC

Perfex Corporation

Pestle

Pevco

phactMI

Pharma Logistics, LLC

Pharma Source Direct

Pharmacists Mutual Insurance Company

PharmaComplete

Pharmacy Automation Supplies

Pharmacy Brokers

Pharmacy Consulting Broker Services

Pharmacy First

Pharmacy Podcast Network

Pharmacy Quality Alliance (PQA)

Pharmacy Quality Solutions (PQS)

Pharmacy Stars, LLC

Pharmacy Technician Certification Board (PTCB)

Pharmacy Times (MJH Life Sciences)

Pharmacy-Lite Packaging

PharmaForce

PharmaLink Inc.

Pharmapod

PharmaPoint, LLC

Pharmathek

PharmCon

PharmEcology (WM)

Pharmetric Laboratory

PharmID, Inc.

Pharmsource, LLC

PharmWaste Technologies, Inc.

PHC Corporation of North America

Phox Health, Inc

Pillr Health

Pine Pharmaceuticals

PK Telehealth (TCE Group)

Plenful

PointClickCare

Powerpak (Postgraduate Healthcare Education)

PPOk

PreciseRX

Precision Dose, Inc.

Premier

Prescryptive Health, Inc.

Primex Inc.

Prompt Praxis Laboratories

ProPharma Cleanrooms

ProxsysRx

PRS Pharmacy Services

Prudential Cleanroom Services

Pure Microbiology, LLC

Pyrls (Cosmas Health, Inc)

Q.I. Medical Inc

QleanAir Scandinavia

QRx Solutions

QuicksortRx, Inc.

QuidelOrtho Corporation

QuVa Pharma

R.C. Smith

R.J. Hedges & Associates

R&S Northeast LLC

RD Plastics Company, Inc.

Real Value Rx

Redsail Technologies, LLC

Rees Scientific

Relay Robotics, Inc.

Retail Designs Inc.

Retail Management Solutions, LLC

Return Solutions, Inc.

Revelation Pharma

RevSpring, Inc.

Roemer Industries

RPh on the Go

Rx Advisors

RX Destroyer

Rx relief

Rx Return Services, LLC.

Rx Reverse Distributors, Inc.

Rx Systems, Inc.

Rx2Go

RxConnexion

RxDispense

RXinnovate Consulting

RXinsider

RxLive, Inc.

RxMile

RxOwnership (McKesson)

RxPreferred

RxRise

RxScan

RXshelving.com (Surplus Equipment Company)

Safecor Health

Samson Medical Technologies, LLC

Sanford Guide

SCA Pharma

ScriptPro LLC

SDS Rx

SensoScientific, Inc.

ServRx, Inc.

Shamrock Labels

Sharps Medical Waste Services

Shepard Medical Products

Shields Health Solutions

Skyline Pharmaceuticals

SmartCells (SATECH, Inc.)

SmartSense (Digi International)

Smith Drug Company

So-Low Environmental Equipment Co.

SoftWriters, Inc

Soliant Health

Source Communications LLP

South Pointe Wholesale, Inc.

SpecializedRx Products, LLC

Specialty Medical Staffing

Spectrum Pharmacy Products

Speed Script

SpendMend

Sphinx Strategies

SpotSee

SRS Pharmacy Systems

STACK, LLC

STAQ Pharma, Inc.

STChealth

Stericycle, Inc. (WM)

Stratix Labs Corporation

SuiteRx, LLC

Suncrest Solutions

SUNRx

SureCost, LLC

Surescripts

Swisslog Healthcare

Sykes & Company, P.A.

TailorMed

TEAM Technologies, Inc.

Teknipure

TelNet-Rx

Tension Packaging & Automation

Terso Solutions, Inc.

Texwipe (ITW)

The Baker Company

The Compliance Team, Inc.

The Craneware Group

The Medicine Shoppe Pharmacy

The Relief Products

Thermo Fisher Scientific, Inc.

ThoroughCare, Inc.

TICKERWORKS

TopRx, LLC

Total Pharmacy Supply, Inc.

Total-Shield PLUS (McGowan Industries, Inc.)

TouchPoint Medical

TraceLink, Inc.

TrackTraceRx, Inc.

Trane Technologies

TransferMyRx

Travis CleanAir, Inc.

TRC Healthcare

Trilogy MedWaste, Inc.

TruMed Systems, Inc.

Turbare Manufacturing

U.S. Micro-Solutions, Inc.

UGO

Unidoses

United Pharmacy Network (UPN)

UNITED Staffing Network, Inc.

United States Pharmacopeia (USP)

UNIWEB, Inc.

Updox by EverHealth

Value Drug Company

Veltek Associates, Inc.

Veracity Group, Inc.

Veridikal

Verity Solutions

Vileda Professional

Virtue Technologies

Visante

VIVID (Scientific Industries, Inc.)

Vizient, Inc.

VMI Care

VPL, Inc.

WeInfuse, LLC

Well-Served Pharmacy Community (WSPC)

Wellgistics

Wellpartner

Wells Pharma

West Pharmaceutical Services, Inc.

Winfield Laboratories Inc

Wolters Kluwer

Workflow Services

WorkingBuildings

Yardi Systems, Inc.

Yukon Medical, LLC

Yuyama USA, Inc.

Zebra Technologies Corp.

340B Health

340BDirect | Procuity

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