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Pharmacy500 IVR and Patient Communications Systems Report 2025

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JUN 2025

SUPPLY CHAIN TEARDOWN

IVR & PATIENT

COMMUNICATION SYSTEMS

Report Lead

Emma Cidade

MEET THE

MARKET INTELLIGENCE TEAM

About RXinsider

Founded in 1999, RXinsider is a pharmacist-founded marketing/

communications (MARCOM) and market intelligence (INTEL) company

focused on pharmacy operations and the companies supporting

dispensing pharmacies. Through our publications, digital platforms,

market research, and training resources, RXinsider educates pharmacy

management and industry professionals on the products, services,

and trends that impact pharmacy operations across the supply chain.

RXinsider’s Market Intelligence (INTEL) Group performs market research

on the pharmacy operations supply chain and the Pharmacy500

companies. Through our weekly reports, digital awareness, and online

training, the INTEL Group educates Pharmacy500 professionals and

pharmacy management on the products and services impacting

pharmacy operations.

Alexa DiLuca

Marketing Manager

Gregory Cianfarani, RPh

Founder & CEO

Jeff Rackliff

Pharmacy500 Market Analyst

jeff.rackliff@rxinsider.com

Emma Cidade

Pharmacy500 Market Analyst

emma.cidade@rxinsider.com

Lexi Cianfarani

Pharmacy500 Market Analyst

lexi.cianfarani@rxinsider.com

Table of Contents

• Introduction .............................................................2-3

• Executive Snapshot ...................................................4

• Overview & Key Features ..........................................5

• Company Listing ........................................................6

• Companies by Region & Practice Settings ............7

• Product Matrix ............................................................8

• Conferences, Trade Shows & Meetings ...........9-11

• End Users & Buyer Personas ................................ 12

• Supply Chain Crossover .......................................... 13

• Career Center ........................................................... 14

• References ................................................................ 15

• Pharmacy500 Companies ............................... 16-19

A 2025 Breakdown of IVR and Patient

Communication Systems Companies and Trends

The objective of this report is to educate Pharmacy500

professionals, pharmacy leadership, and other stakeholders on

key trends within the supply chain as it relates to Interactive Voice

Response (IVR) and patient communication systems.

Pharmacy500 companies

offer Interactive Voice

Response Systems.

Pharmacy500 companies

that offer IVR systems

also offer PMS.

18,984

Independent community

pharmacies in the U.S. as of 2024.

3,200

Specialty pharmacies in the U.S.

as of December 2024.

$9.27B is the projected amount that the international IVR market will reach in 2030

(compared to $6.44B in 2025).

Source: NCPA

Source: De�nitive Healthcare

Source: RXinsider

EXECUTIVE SNAPSHOT

IVR & PATIENT

COMMUNICATION

SYSTEMS

50%

Reduced call volume in

pharmacies that have

implemented IVR.

Source: SRS Pharmacy

Systems

IVR exhibitors at

NCPA in 2024

Source: RXinsider

Source: Research and

Markets

IVR System Overview

A pharmacy IVR (Interactive Voice Response) system is an automated telecommunication

technology used by pharmacies to interact with customers or patients through pre-recorded

voice prompts and menus. The system allows patients or customers to perform a variety of

tasks related to prescription management and pharmacy services without the need for direct

interaction with a pharmacy staff member.

It improves operational ef�ciency, enhances patient convenience, and reduces the workload

on pharmacy staff, while providing patients with 24/7 access to important services. When

well-integrated and user-friendly, an IVR system can signi�cantly improve both pharmacy

operations and the overall patient experience.

Key Features and Functions

1. Prescription Re�lls:

The most common use of an IVR system in pharmacies is for handling prescription re�ll requests. Patients can call the pharmacy, navigate through the

IVR menus, and request re�lls for their prescriptions by entering relevant information, such as prescription numbers or personal identi�cation details.

2. Appointment Scheduling and Noti�cations:

Some IVR systems allow patients to schedule appointments for services like vaccinations, health screenings, or consultations. Additionally, the system

can provide reminders about upcoming appointments or when prescriptions are ready for pickup.

3. Medication Alerts:

IVR systems can deliver automated reminders or alerts to patients about when it’s time to re�ll their medications, take their medication, or pick up their

prescriptions. This helps ensure medication adherence.

4. Order Status and Prescription Tracking:

Patients can check the status of their prescription orders, such as whether their medication is ready for pickup or still being processed. The system

can notify patients when their prescriptions are ready for collection or if there are any issues with their order.

5. Patient Information and Pro�le Updates:

Some IVR systems allow patients to update or con�rm their personal information, such as phone numbers, addresses, or insurance details, ensuring

that the pharmacy’s records are up-to-date for better service.

6. Customer Service Requests:

The IVR system can route patients or customers to the appropriate pharmacy staff for more complex inquiries or assistance, such as clarifying dosage

instructions, explaining insurance coverage, or addressing billing questions.

7. Payment Processing:

Some IVR systems allow patients to make payments over the phone, either for prescriptions or other pharmacy services. Payment can be processed

through secure payment gateways integrated into the IVR system.

8. 24/7 Availability:

One of the primary advantages of an IVR system is its ability to provide around-the-clock access to pharmacy services. Patients can interact with the

pharmacy at any time, even when the pharmacy is closed or during off-hours.

9. Multilingual Support:

Advanced IVR systems may offer support for multiple languages, ensuring that patients from diverse backgrounds can access services in their

preferred language.

10. Integration with Pharmacy Management Systems:

The IVR system is often integrated with the pharmacy’s pharmacy management system (PMS) or electronic health record (EHR) systems, allowing it

to access and update patient pro�les, prescription histories, and order statuses in real-time.

Pharmacy500 IVR System Companies

Advance Net Health Solutions

CarePoint

CPS Solutions, LLC

Cypress Software, Inc.

Datascan Pharmacy, Inc.

DRX SOFTWARE LLC

EnlivenHealth

Epic Systems Corporation

Isak Computing

(SiCompounding & SiPrescribe)

Keycentrix, LLC

Liberty Software

LifeFile

Lumistry

Medtel Communications (Lumistry)

McKesson Corporation

Optum

Outcomes

PCCA

PrimeRx

RedSail Technologies, LLC

ScriptPro LLC

SoftWriters, Inc.

Speed Script

SRS Pharmacy Systems

XiFiN Pharmacy Solutions

The “Pharmacy500” are 500 businesses and associations that signi�cantly

impacted the business operations of dispensing pharmacies in the

U.S. over the previous year. The 25 companies listed below are the

companies within the 2025 Pharmacy500 that make up IVR and patient

communication systems supply chain. For Pharmacy500 criteria and

details, please visit www.RXinsider.com/the-Pharmacy500.

20 %

NORTHEAST

MIDWEST

Companies by Region

This chart outlines the distribution of

Pharmacy500 companies that offer IVR

solutions across the following primary

practice

settings:

Community/Retail,

Hospital/Health

System,

Specialty,

Managed Care/PBM, Long-Term Care,

Home Infusion & Compounding, and

Nuclear.

WEST

8 %

SOUTH

60 %

NUCLEAR

MANAGED CARE / PBM

HOME INFUSION / COMPOUNDING

HOSPITAL / HEALTH SYSTEM

LONG TERM CARE

SPECIALTY

COMMUNITY / RETAIL

13 13

Practice Setting

Breakout

12 %

IVR & Patient Communication Systems Matrix

AdvanceNet Health Solutions

ePostRx

Retail

CarePoint

GuardianRx

Retail

CPS Solutions, LLC

Telepharmacy

Retail, Hospital

Cypress Software, Inc.

RxBLU IVR

Retail

Datascan Pharmacy, Inc.

IVR & Robotic Pharmacy

Prescription Dispensing System

Retail

DRX SOFTWARE LLC

DRX

Compounding, LTC

EnlivenHealth

Personalized Interactive Voice

Response (IVR)

Retail

Epic Systems Corporation

My Chart

Hospital

Isak Computing

(SiCompounding &

SiPrescribe)

Vow TalkRx Support

Retail

Keycentrix, LLC.

SendKey

Retail

Liberty Software

PharmacyOne

Retail

LifeFile

Patient Portal / IVR Services

Retail

Lumistry

LUMISTRY IVR & TELEPHONE

Retail

Medtel Communications

(Lumistry)

Pharmacy Phone Systems

Retail

McKesson Corporation

EnterpriseRx

Retail

Optum

Enterprise Pharmacy System

Retail

Outcomes

Outcomes® IVR

Retail

PCCA

PK Software/TheCompounderRx

Retail

PrimeRx

PrimeCOMM

Retail

RedSail Technologies, LLC

PioneerRx

Retail

BestRx

Retail

NRx (QS/1)

Retail

Axys LTC

LTC

PrimeCare

LTC

ScriptPro LLC

ScriptPro PMS

Retail, Hospital

SoftWriters, Inc.

FrameworkLTC

LTC

Speed Script

Speed Script PRM

Retail

SRS Pharmacy Systems

IVR

Retail

XiFiN Pharmacy Solutions

Fusion-Rx

Retail

PRODUCT NAME

PRIMARY SETTING

PHONE

TEXT

ON-DEMAND ACCESS

COMPANY NAME

Conferences, Trade Shows & Meetings

The following identi�es the major

national pharmacy conferences at

which IVR and patient communication

systems Pharmacy500 companies

exhibited in the past year.

The top two conferences in the

last year were Cardinal Health RBC

and NCPA Annual Convention.

Top Two

Conferences

Cardinal Health RBC

NCPA

2022

2024

2023

2022

2024

2023

MIDYEAR

WINTER

PHARMACY

FUTURES

340B Health | 340B Coalition Summer

Conference

340B Health | 340B Coalition Winter

Conference

Washington, DC

San Diego, CA

JUL 21-23, 2025

FEB 9-11, 2026

1,500+

2,000+

50+

30+

Hospital / Health

System

Membership

AACP | INitiate Interim Meeting

AACP | Pharmacy Education Conference

San Juan, PR

Chicago, IL

FEB 14-17, 2026

JUL 19-22, 2025

300+

2,500+

<10

60+

20+

150+

Academia

Membership

AAP | Annual Conference

TBD

TBD 2026

Undisclosed

55+

<10

Community/Retail

Membership

ACA | Annual Conference & Expo

Memphis, TN

SEPT 25-27, 2025

Undisclosed

10+

Home Infusion &

Compounding

Membership

ACCP | Annual Meeting

Minneapolis, MN

OCT 18-21, 2025

1,500+

Undisclosed

100+

Hospital / Health

System

Membership

ACHC | ACHCU Academy

Amelia Island, FL

MAR 2-4, 2026

Undisclosed

30+

70+

Various

Users/Customers

ACVP | Veterinary Pharmacy Conference

Fort Worth, TX

JUL 24-26, 2025

80+

Community/Retail

Membership

AMCP | Annual Conference

AMCP | Nexus

Nashville, TN

National Harbor, MD

APR 13-16, 2026

OCT 27-30, 2025

4,000+

2,500+

70+

40+

30+

Managed Care/

PBM

Membership

American Pharmacies | APEX Conference

San Antonio, TX

JUN 19-21, 2025

200+

40+

<10

Community/Retail

Users/Customers

APC | Compounders on Capitol Hill

APC | Owner Summit

Washington, DC

Austin, TX

SEPT 16-17, 2025

MAR 19-21, 2026

150+

160+

30+

40+

10+

Home Infusion &

Compounding

Membership

APCI | Annual Convention and Stockholders

Meeting

Louisville, KY

MAR 6-8, 2026

200+

20+

Community/Retail

Membership

APhA | Annual Meeting & Expo

Los Angeles, CA

MAR 27-30, 2026

4,000+

100+

160+

Various

Membership

ASCP | Annual Meeting & Exhibition

San Diego, CA

OCT 23-26, 2025

1,000+

60+

50+

Long Term Care

Membership

Asembia | AXS Summit

Las Vegas, NV

APR 26-30, 2026

8,000+

170+

70+

Specialty

Users/Customers

ASHP | Midyear

ASHP | Pharmacy Futures

Las Vegas, NV

Charlotte, NC

DEC 7-11, 2025

JUN 7-11, 2025

20,000+

1,500+

340+

90+

200+

20+

Hospital / Health

System

Membership

Cardinal Health | RBC

Denver, CO

JUL 9-12, 2025

4,500+

200+

30+

Community/Retail

Users/Customers

Cencora | ThoughtSpot

Las Vegas, NV

JUL 16-19, 2025

3,500+

500+

20+

Various

Users/Customers

CORE Higher Education Group | Annual

Summit

Providence, RI

SEPT 29 -

OCT 1, 2025

100+

<10

Academia

Users/Customers

DiversifyRx | Pharmacy Pro�t Summit

Dallas, TX

MAR 28-29, 2026

350+

100+

10+

Community/Retail

Users/Customers

Epic | UGM

Epic | XGM

Verona, WI

TBD

AUG 18-21, 2025

TBD

Undisclosed

10+

20+

Hospital

/ Health

System

Users/

Customers

Epicor | Insights

Nashville, TN

MAR 18-21, 2026

3,000+

Undisclosed

40+

Community/Retail

Users/Customers

GeriMed | Annual Conference

Marco Island, FL

NOV 7-8, 2025

Undisclosed

Long Term Care

Users/Customers

HCP | Fall Hospital Pharmacy Conference

HCP | Spring Hospital Pharmacy Conference

Chicago, IL

TBD

SEPT 29 -

OCT 1, 2025

TBD

Undisclosed

Hospital / Health

System

Users/Customers

Pharmacy500 Conferences

ATTENDEES

(Approx.)

EXHIBITORS

(Approx.)

EDUCATION

SESSIONS

(Approx.)

LOCATION

DATE

ATTENDEE

TYPE

SETTING

FOCUS

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20