MAY 2025
SUPPLY CHAIN TEARDOWN
PHARMACY MANAGEMENT
SYSTEM (PMS) SOFTWARE
©2025 RXinsider | RXinsider Market Intelligence Group | 2025
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MARKET INTELLIGENCE TEAM
About RXinsider
Founded in 1999, RXinsider is a pharmacist-founded marketing/
communications (MARCOM) and market intelligence (INTEL) company
focused on pharmacy operations and the companies supporting
dispensing pharmacies. Through our publications, digital platforms,
market research, and training resources, RXinsider educates pharmacy
management and industry professionals on the products, services,
and trends that impact pharmacy operations across the supply chain.
RXinsider’s Market Intelligence (INTEL) Group performs market research
on the pharmacy operations supply chain and the Pharmacy500
companies. Through our weekly reports, digital awareness, and online
training, the INTEL Group educates Pharmacy500 professionals and
pharmacy management on the products and services impacting
pharmacy operations.
Alexa DiLuca
Marketing Manager
Gregory Cianfarani, RPh
Founder & CEO
Jeff Rackliff
Pharmacy500 Market Analyst
jeff.rackliff@rxinsider.com
Emma Cidade
Pharmacy500 Market Analyst
emma.cidade@rxinsider.com
Lexi Cianfarani
Pharmacy500 Market Analyst
lexi.cianfarani@rxinsider.com
Report Lead
Jeff Rackliff
©2025 RXinsider | RXinsider Market Intelligence Group | 2025
A 2025 Breakdown of Pharmacy Management
System (PMS) Software Companies and Trends
Table of Contents
• Introduction .............................................................2-3
• PMS Executive Snapshot ..........................................4
• PMS Overview & Key Features ................................5
• PMS Company Listing ...........................................6-7
• Company Location & Practice Setting ...................8
• Company Size..............................................................9
• Market News ............................................................ 10
• Product Matrix ......................................................... 11
• Conferences, Trade Shows & Meetings .............. 12
• Pharmacy500 Conferences ............................ 13-14
• PMS End-Users & Buyer Personnas ..................... 15
• Supply Chain Crossover .......................................... 16
• References .......................................................... 17-18
• Pharmacy500 Companies ............................... 19-22
The objective of this report is to educate Pharmacy500
professionals, pharmacy leadership, and other stakeholders
on key trends within the supply chain as it relates to pharmacy
management system software platforms.
The “Pharmacy500” are 500 businesses and associations
that
signi�cantly
impacted
the
business
operations
of
dispensing pharmacies in the U.S. over the previous year.
There are 24 companies within the 2025 Pharmacy500
that make up the pharmacy management systems supply
chain category. For Pharmacy500 criteria and details, please
visit www.RXinsider.com/the-Pharmacy500.
©2025 RXinsider | RXinsider Market Intelligence Group | 2025
24
Pharmacy500 companies
offer PMS software
PMS software mergers
and acquisitions
since 2020
18,984
Independent community pharmacies
in the U.S.as of 2024.
3,200
Specialty pharmacies in the U.S. as
of December 2024.
Pharmacy500 PMS
companies host user
conferences
6,093 hospitals in the U.S. as of 2025.
Source: NCPA
Source: De�nitive Healthcare
Source: RXinsider
Source: RXinsider
Source: RXinsider
EXECUTIVE SNAPSHOT
PHARMACY MANAGMENT
SYSTEM (PMS) SOFTWARE
Source: American Hospital Association
©2025 RXinsider | RXinsider Market Intelligence Group | 2025
Pharmacy Management System (PMS)
Software Overview
Pharmacy Management System (PMS) software is a specialized software
solution designed for pharmacies to ef�ciently manage their operations,
work�ows, and enhance patient care. It integrates various aspects of
pharmacy technology and operations into a centralized platform, enabling
pharmacists and staff to handle tasks effectively and accurately. The PMS
functions as the “brain” of the pharmacy.
Key Components of a PMS
1. Patient Pro�le Management
• Maintains patient records, including prescription
history and allergies.
• Enables personalized medication reminders and
consultations.
2. Prescription Processing
• Handles electronic prescriptions
(e-prescriptions).
• Ensures proper dosage and medication
dispensing.
• Checks for drug interactions and
contraindications.
3. Integration with Other Pharmacy Technology
• POS System
• IVR System
• Ful�llment Robots
• Tablet Counters
• Printers
• EHR
• eMAR
4. Inventory Management
• Tracks medication stock levels.
• Alerts for low inventory or expired drugs.
• Automates ordering from suppliers.
5. Compliance and Regulatory Support
• Ensures compliance with local and national drug
regulations.
• Supports audit trails and reporting for authorities.
6. Third-Party Integrations
• Connects with healthcare systems, insurance
providers, and suppliers.
• Facilitates claims processing and
reimbursement.
7. Reporting and Analytics
• Provides insights into sales, inventory, and
operational performance.
• Helps in decision-making and forecasting.
Pharmacy500 PMS Companies
©2025 RXinsider | RXinsider Market Intelligence Group | 2025
©2025 RXinsider | RXinsider Market Intelligence Group | 2025
©2025 RXinsider | RXinsider Market Intelligence Group | 2025
25%
NORTHEAST
MIDWEST
Companies by Region
This chart outlines the distribution
of Pharmacy500 PMS companies
across
the
following
primary
practice settings: community/retail,
hospital/health system, specialty,
managed care/PBM, long-term care,
home infusion & compounding, and
nuclear.
WEST 17%
SOUTH
50%
21
13
10
13
Practice Setting Breakout
8%
NUCLEAR
MANAGED CARE / PBM
HOME INFUSION / COMPOUNDING
HOSPITAL / HEALTH SYSTEM
SPECIALTY
LONG TERM CARE
COMMUNITY / RETAIL
©2025 RXinsider | RXinsider Market Intelligence Group | 2025
1,000+ EMPLOYEES
201-1,000 EMPLOYEES
51-200 EMPLOYEES
1-50 EMPLOYEES
Companies by Size
The Pharmacy500 companies offering PMS software
range in size. There are 5 small companies with less
than 50 employees, 5 medium-sized companies with 51
to 200 employees, 5 large companies with 201 to 1,000
employees, and 9 very large organizations with more than
1,000 employees.
10
PMS Market News
PCCA | Names Chief Scienti�c Of�cer Gus Bassani, PharmD, as CEO
RedSail Technologies | Announces Acquisition of Emporos
RedSail Technologies | Launches RedSail Pay, a Comprehensive Merchant Services Solution
PrimeRx | Announces First User Conference to be Held in October
Keycentrix | Announces Strategic Partnership with UST
PrimeRx | Announces PrimeRx Market
Oracle Health | Announces new AI-Powered electronic health record
Keycentrix | Announces IntelligentPA, Powered by CoverMyMeds, in Newleaf®
RedSail Technologies | Announces Aquisition of BestRx
PrimeRx | Announces PrimeRx Cloud
Q1|
2025
Q4|
2024
Q2|
2024
©2025 RXinsider | RXinsider Market Intelligence Group | 2025