20Ways Spring Retail 2026

Improving Patient Care & Pharmacy Profitability

SPRING 2026 I RETAIL/COMMUNITY • SPECIALTY • LTC

26

Q. Specialty pharmacy continues to dominate

healthcare headlines. Why is this segment so

important right now?

Most healthcare leaders don’t realize that 80% of the drugs

in the pipeline are IV-formulations with specialty indications,

and that no pharmacies are getting access to the downstream

oral versions if they can’t prove their capabilities or partner on

launch today. I can’t emphasize this enough for providers that

are still thinking about specialty or infusion — it is existential for

pharmacy survival moving forward. Specialty patients represent

a relatively small portion of the overall population, yet they drive

a disproportionate share of drug spend and resource intensity

across the healthcare system.

That reality changes the stakes. However, I won’t sugarcoat the

reality that it is not easy to compete in this space. Everyday in

this field, small operational breakdowns can create outsized

consequences — lost margin, denied claims, strained payer

relationships, audit vulnerability, limited-distribution access

issues, and stalled growth. At the same time, organizations that

build the right foundation can unlock meaningful enterprise

value. That is why many pharmacy leaders are seeking

experienced guidance early, before complexity turns into costly

rework.

Q. What makes specialty and infusion pharmacy

so different from traditional pharmacy operations?

Traditional pharmacy is often driven by prescription volume

and dispensing efficiency. Specialty and infusion pharmacy are

driven by infrastructure, coordination, and precision. These

models require far more than filling prescriptions well.

Operators must navigate accreditation standards, payer and

manufacturer expectations, multi-state licensure, infusion and

nursing coordination, cold-chain and hazardous shipping

protocols,

clinical

documentation,

prior

authorization

workflows, inventory controls, referral capture, and increasingly

sophisticated reporting requirements. Success depends on

whether these moving parts are built into the operating model

from the beginning. When organizations try to bolt them on later,

growth often outpaces control.

Q. How do experienced consultants help

organizations navigate that level of complexity?

The most effective advisors do more than provide recommendations.

They help organizations translate strategy into execution across

several interconnected areas: operations, financial performance,

regulatory readiness, and market growth.

That may include designing accreditation-ready workflows,

building scalable staffing models, assessing payer and trade

strategy, evaluating service-line expansion opportunities,

strengthening referral conversion processes, supporting multi-

state compliance, and creating practical dashboards that connect

daily performance to long-term financial goals. The best

consulting support is not theoretical. It gives leadership a clearer

roadmap, stronger controls, and measurable improvement in

both revenue performance and risk reduction.

Q. At what stage in a pharmacy or infusion

pharmacy’s growth journey is outside guidance

most valuable?

Usually earlier than leaders think. The need often begins before

launch, during expansion planning, ownership transition,

specialty service-line development, infusion build-out, or entry

into new payer and manufacturer relationships. It also becomes

critical when a pharmacy is preparing for accreditation, scaling

into multiple states, adding nursing or clinical programs,

evaluating technology changes, or trying to improve profitability

without sacrificing compliance.

Many organizations wait until there is a failed audit, payer friction,

margin compression, staffing instability, or referral leakage.

By then, the work is often more expensive and more disruptive.

The strongest outcomes usually happen when leadership brings

in experienced support during key inflection points, while there

is still room to design intentionally rather than react defensively.

Q. What are the most common gaps that hold

specialty and infusion pharmacies back?

A few patterns show up repeatedly. Outside of the reimbursement

pressures and industry dynamics that affect all independents,

one common gap is the lack of alignment between operations

and financial modeling. Another is treating compliance as

a separate function instead of embedding it into workflows,

staffing, training, and reporting. This misunderstanding can lead

to “operational diverticulitis” where credentialing, patient flow,

documentation, inventory, contracting, and quality management

all operate in silos instead of harmoniously.

There is also often a business development gap. Pharmacies

may have strong clinical capability but weak referral strategy,

inconsistent provider engagement, unclear value messaging,

VIC SIMIANU, MBA, PRINCIPAL, FOUNDER AT SPHINX STRATEGIES

QUESTION & ANSWER

SPECIALTY